Acomplia (rimonabant) was developed and tested by Sanofi-Aventis, a global pharmaceutical company. Acomplia (Rimonabant) was launched on to the European market in 2006, and won approval from the European regulators on the basis of major clinical double-blind, randomised, placebo-controlled trials involving thousands of participants. The results showed that one third of the participants taking acomplia lost an average of twenty pounds over a period of one year. The researchers demonstrated that those who take acomplia may realistically expect to lose 10% of their weight and, with a proper diet and physical exercise, should maintain that reduced weight for one year. The studies also measured the circumference of each participant’s waist and found an average reduction of about 3 inches. Further, the level of HDL — the good cholesterol — rose and the level of triglyceride decreased which improves the health outlook for those at risk of heart disease. Because blood glucose was better regulated, it can help anyone with diabetes to lose weight safely and improve the levels of sugar and fat in their blood.

Now with acomplia (rimonabant) routinely prescribed, the everyday evidence shows acomplia (rimonabant) as a highly effective treatment for those who carry excessive weight, not only enabling you to lose some of that weight, but also improving your health so that you are less at risk of heart disease, diabetes and other weight-related problems. As a result, acomplia (rimonabant) is becoming the medication of choice for those who want to lose weight.

Acomplia (rimonabant) works by blocking the brain’s messaging system that would normally tell you to eat, i.e. it suppresses those hunger pangs. When you combine acomplia with a low calorie diet and maintain a regular program of light exercise, you will find you can lose weight quickly and safely.

Acomplia (rimonabant) also reduces your desire for addictive substances like nicotine. Research has shown that smokers who take acomplia are more likely to quit smoking and to do so without the usual weight gain that is often associated with quitting.

The generic name for acomplia is rimonabant. Sanofi-Aventis has registered the trademark zimulti for use in the United States. The manufacturer is currently conducting a further series of trials, and collecting data from those who participated in the initial trials so that evidence over two or three years can be collected. When all the new evidence is collated and analysed, it is expected that Sanofi-Aventis will resume its application for approval for acomplia (rimonabant) in the United States..

Acomplia is a medication that suppresses your appetite and, if you are overweight, it helps you to lose that weight safely and then keep it off. Acomplia works by modifying the messaging system in your brain so that you do not recognise the usual hunger signals. Acomplia also reduces the cravings for nicotine and helps smokers to give up smoking. There is some evidence that acomplia may reduce the risk factors for cardiovascular disease and it may improve the body’s regulation of blood glucose and cholesterol levels.

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Acomplia works inside the Endocannabinoid System. The brain depends on the neurotransmitters to carry messages from one part of the brain to another. The cannabinoids (including CB-1) are naturally produced chemicals that form a part of the brain’s system for offering rewards when you do something the body likes. Thus, its function is not simply to carry messages about hunger (i.e. tell you when the body says it needs more fuel to keep it running). It also triggers the release of dopamine when you eat food that the body likes. Acomplia blocks the CB-1 receptors. Thus, not only does it slow the messages that would trigger your appetite, it also denies you some of the pleasure you derive from the activity of eating. The clinical data suggests that the Endocannabinoid System is overactive in people who are overweight. Your hypothalamus is therefore bombarded with hunger signals. Because acomplia damps down this messaging system, you feel less hungry, so you eat less and lose weight safely and effectively.

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Because the Endocannabinoid System not only helps to regulate appetite, but also forms a part of the pleasure centre within the brain, acomplia can help you to resist cravings. By denying you some of the pleasure from the activity, it can support your decision to give up smoking. Among the participants in the clinical trials into the use of acomplia for weight loss were a number of smokers. They reported that they were able to quit while taking acomplia. This has a beneficial side effect. When some people stop smoking, they put on weight. Taking acomplia avoids this problem.

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It is almost impossible to produce an effective medication that does not cause side effects for some of those who take it. In comparison with other appetite suppressants. Acomplia’s side effects are mild. The most common of these effects are dizziness, nausea, anxiety or depression. Most of these effects are not troublesome and they fade as your body adapts to acomplia.

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In the countries where the regulators have approved the use of acomplia, its use is restricted to those who have a body mass index (BMI) of 30 or higher, or for those who have BMI 27 or higher but also have cardiovascular problems, diabetes or other medical problems putting their health more directly at risk. Acomplia is used off-label for those who want to give up smoking.

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Your body digests medications in the stomach and absorbs them into the blood stream. In due course, they are picked up as they pass through the kidneys and excreted. If you have any problems with your kidneys or liver this can lead to acomplia remaining in your body for too long.

Because one of the side effects of taking acomplia is that it can make some people depressed, you should not start taking it if you are already suffering from an anxiety disorder or depressive illness. This warning is particularly important because many people who are overweight are depressed about their condition. It is very important that you discuss the effects of acomplia with your physician before beginning to take it.

The clinical trials for acomplia have not included all age ranges. There are no data on safety and effectiveness for people aged less than nineteen or more than 75 years. Similarly, neither epileptics nor pregnant women have been included in acomplia trials. If you fall into any of these classes, you should discuss the possible risks with your physician.

The manufacturing process for acomplia tablets includes lactose. If you have any kind of lactose intolerance, you should not take acomplia.

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The results from placebo-controlled clinical trials have shown that one third of the participants who took acomplia in a daily dose of 20mg lost an initial 20 pounds and an average 10% of their total body weight at the end of their first year. They were then able to maintain the reduced weight for a further year. These results were obtained by using acomplia alongside a low calorie diet.

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There are a number of medications that can interact with acomplia to produce adverse side effects. Before you begin taking acomplia, it is important to give your physician a comprehensive list not only of the prescription medications you take, but also all the non-prescription health supplements, vitamins and other herbal remedies you take.

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The standard acomplia tablet is supplied at 20mg which should be taken once daily before eating breakfast. To reduce the risk of side effects, you should swallow the tablet whole with plenty of water. Do not crush or chew the tablets.

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